Blocked functional reagants for cross-linking biological tissues
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United States of America Patent
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Jan 23, 2001
Grant Date -
N/A
app pub date -
Apr 9, 1999
filing date -
Apr 9, 1999
priority date (Note) -
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Abstract
A method for cross-linking biological tissue is provided which uses as a cross-linking agent a low molecular weight, substantially monomeric polyfunctional aldehyde formed in situ or just prior to cross-linking. The polyfunctional aldehyde is essentially free of the undesirable heterogeneous polymeric species that result from polyfunctional aldehyde self-reactivity. Also provided is biological tissue that is cross-linked with a substantially monomeric glutaraldehyde.
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