Enhanced ciruclation effector composition and method
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United States of America Patent
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Jan 30, 2001
Grant Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Mar 23, 1993
priority date (Note) -
In Force
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Abstract
A liposome composition comprising small, surface-bound effector molecules is disclosed. The liposomes have a surface layer of hydrophilic polymer chains, for enhanced circulation time in the bloodstream. The effector molecules are attached to the distal ends of the polymer chains. In one embodiment, the effector is polymyxin B, for treatment of septic shock.
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