Breath test for detection of drug metabolism
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United States of America Patent
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-
Jan 30, 2001
Grant Date -
N/A
app pub date -
Jun 28, 1999
filing date -
Jan 3, 1997
priority date (Note) -
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status (Latency Note)
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Abstract
A breath test for determining the rate of metabolism of a drug is described. First, a safe and effective amount of the drug, preferably appropriately labelled and most preferably isotopically-labelled, is administered to a subject. After a suitable time period, the exhaled breath of the subject is analyzed to determine the concentration of a metabolite. The concentration of the metabolite is then used to determine the rate of metabolism of the drug. A breath test kit is also described. Such a breath test kit would include an item or items necessary for performing at least one of the methods of determining the rate of metabolism of a drug in a subject. For example, such a breath test kit could include an isotopically-labelled drug to be administered to the subject.
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