Use of purine receptor agonists to alleviate or normalize physiopathologically excited sensory nerve function
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United States of America Patent
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Jan 30, 2001
Grant Date -
N/A
app pub date -
Dec 7, 1999
filing date -
May 10, 1990
priority date (Note) -
Expired
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Abstract
A method for the alleviation or normalization (i.e., treatment) of physiopathologically excited sensory nerve function (i.e., pain) comprising the administration of a purine receptor agonist in an effective amount to a mammal other than a rodent. In a preferred embodiment, pain is treated in a human by the administration of an effective amount of a purine receptor agonist. In an alternative embodiment, an adenosine compound, such as but not limited to adenosine or adenosine triphosphate, is administered in an effective amount to a human to treat surgical pain, chronic pain, and/or traumatic pain. Human patients receiving a continuous infusion of an adenosine compound during surgery reported a profound analgesic effect after surgery.
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