Soft x-ray emitting radioactive stent
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United States of America Patent
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Feb 6, 2001
Grant Date -
N/A
app pub date -
Feb 9, 1999
filing date -
Feb 10, 1998
priority date (Note) -
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Abstract
An implantable medical device according to the present invention comprises a body, such as a stent or a wire, and an isotope having a high neutron activation cross-section, such as .sup.168 Yb or .sup.124 Xe, ion-implanted onto the surface of the body. The use of isotopes having high neutron activation cross-sections allows a wider choice of substrates to be employed, including stainless steel, nickel, titanium, and alloys including these metals, because the time required for neutron activation of the device is reduced. A coating of high-density material may be incorporated to serve several useful purposes, including containment of undesirable beta particles from long-lived radioactive species, creation of a biologically inert surface, and enhancement of x-ray radiopacity to improve the visibility of an implanted medical device. The implantable medical devices of the present invention also comprise radioactive medical devices which include radioisotopes such as .sup.169 Yb and .sup.125 I.
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