US Patent No: 6,183,518

Number of patents in Portfolio can not be more than 2000

Method of replacing nucleus pulposus and repairing the intervertebral disk

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Importance

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Abstract

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A process for repairing the annulus fibrosus, and replacing the nucleus pulposus. Removal of the nucleus pulposus and only as much of the annulus fibrosus and intervertebral disk as is necessary is performed. The tissue so removed is replaced by a material which is resilient, but non-dispersing upon setting. After application of the material, and after the material is set, the resiliency of the material permits motion of the vertebrae and performs the cushioning and joint functions of the intervertebral disk. The material is physiologically acceptable to the human body.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
NUVASIVE, INC.SAN DIEGO, CA262

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Guagliano, Peter A 370 Bay Ridge Pkwy., Brooklyn, NY 11209 11 650
Ross, Anthony C 3546 Maybank Hwy., John's Island, SC 29455 19 684

Cited Art Landscape

Patent Info (Count) # Cites Year
 
HOWMEDICA OSTEONICS CORP. (2)
* 5,047,055 Hydrogel intervertebral disc nucleus 651 1990
* 5,800,549 Method and apparatus for injecting an elastic spinal implant 261 1997
 
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (1)
* 5,545,229 Functional and biocompatible intervertebral disc spacer containing elastomeric material of varying hardness 372 1993
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (6)
* 6,395,034 Intervertebral disc prosthesis 236 1999
* 2004/0260,397 Method of defect closure in anulus fibrosus 186 2003
* 2004/0249,459 Nucleus replacements with asymmetrical stiffness 5 2004
* 2005/0206,039 Encapsulated intervertebral disc prosthesis and methods of manufacture 28 2005
8,834,496 Soft tissue repair methods and apparatus 0 2011
8,764,835 Intervertebral disc treatment methods and apparatus 0 2011
 
Seminis Vegetable Seeds, Inc. (1)
* 2005/0131,541 Intervertebral disc nucleus implants and methods 55 2005
 
BIOMERIX CORPORATION (2)
7,763,077 Repair of spinal annular defects and annulo-nucleoplasty regeneration 21 2003
7,803,395 Reticulated elastomeric matrices, their manufacture and use in implantable devices 10 2004
 
PIONEER SURGICAL TECHNOLOGY, INC. (3)
7,001,433 Artificial intervertebral disc device 46 2002
8,241,360 Artificial disc device 4 2004
8,262,731 Artificial disc device 0 2005
 
OUROBOROS MEDICAL, INC. (1)
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HOWMEDICA OSTEONICS CORP. (1)
8,197,547 Radiovisible hydrogel intervertebral disc nucleus 0 2005
 
Intrinsic Therapeutics, Inc. (28)
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7,563,282 Method of supporting nucleus pulposus 25 2003
7,727,241 Device for delivering an implant through an annular defect in an intervertebral disc 21 2004
8,002,836 Method for the treatment of the intervertebral disc anulus 1 2004
7,749,275 Method of reducing spinal implant migration 19 2004
7,513,911 Method of implanting dynamically stable spinal implant 48 2004
7,553,329 Stabilized intervertebral disc barrier 58 2004
7,658,765 Resilient intervertebral disc implant 19 2004
8,231,678 Method of treating a herniated disc 5 2006
7,879,097 Method of performing a procedure within a disc 22 2006
7,524,333 Method of anchoring an implant in an intervertebral disc 46 2006
7,500,978 Method for delivering and positioning implants in the intervertebral disc environment 22 2006
7,553,330 Methods of reinforcing an intervertebral disc annulus 33 2006
7,998,213 Intervertebral disc herniation repair 9 2006
7,972,337 Devices and methods for bone anchoring 20 2006
7,959,679 Intervertebral anulus and nucleus augmentation 11 2007
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8,025,698 Method of rehabilitating an anulus fibrosus 9 2009
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8,454,612 Method for vertebral endplate reconstruction 1 2009
8,114,082 Anchoring system for disc repair 18 2009
8,323,341 Impaction grafting for vertebral fusion 1 2009
8,361,155 Soft tissue impaction methods 1 2010
8,409,284 Methods of repairing herniated segments in the disc 2 2011
8,257,437 Methods of intervertebral disc augmentation 5 2011
8,394,146 Vertebral anchoring methods 1 2011
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KAELBELIN, JOHN P. (1)
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KRT INVESTORS, INC. (28)
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7,985,257 Methods and devices for spinal disc annulus reconstruction and repair 7 2006
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7,993,405 Spinal disc annulus repair system and methods 6 2006
7,951,201 Method and apparatus for the treatment of the intervertebral disc annulus 8 2007
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7,905,923 Devices and methods for annular repair of intervertebral discs 3 2007
8,128,698 Method and apparatus for the treatment of the intervertebral disc annulus 4 2008
8,163,022 Method and apparatus for the treatment of the intervertebral disc annulus 2 2009
8,652,153 Intervertebral disc annulus repair system and bone anchor delivery tool 0 2010
8,460,319 Intervertebral disc annulus repair system and method 0 2010
8,556,977 Tissue anchoring system and method 3 2010
9,114,025 Methods and devices for spinal disc annulus reconstruction and repair 0 2011
9,095,442 Method and apparatus for the treatment of the intervertebral disc annulus 0 2012
8,454,697 Method and apparatus for the treatment of tissue 1 2012
 
DISC DYNAMICS, INC. (4)
7,077,865 Method of making an intervertebral disc prosthesis 90 2003
7,001,431 Intervertebral disc prosthesis 163 2003
7,713,301 Intervertebral disc prosthesis 24 2006
7,766,965 Method of making an intervertebral disc prosthesis 42 2006
 
ANULEX TECHNOLOGIES, INC. (1)
8,034,112 Spinal disc annulus reconstruction method and spinal disc annulus stent 6 2006
 
PAUZA, KEVIN (10)
7,235,255 Biological bioadhesive compositions and methods of preparation and use 20 2004
7,229,633 Biological bioadhesive compositions and methods of preparation and use 3 2004
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8,403,923 Injection of fibrin sealant in the absence of corticosteroids in spinal applications 0 2005
8,206,448 Injection of fibrin sealant using reconstituted components in spinal applications 1 2005
7,597,687 Injection of fibrin sealant including an anesthetic in spinal applications 0 2005
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8,403,895 Injection of fibrin sealant including an anesthetic in spinal applications 0 2009
8,394,072 Injection of fibrin sealant including an anesthetic in spinal applications 1 2009
8,986,304 Injection of fibrin sealant using reconstituted components in spinal applications 0 2012
 
KNOBBE MARTENS OLSON & BEAR LLP (1)
8,469,961 Methods and compositions for minimally invasive capsular augmentation of canine coxofemoral joints 8 2009
 
NUVASIVE, INC. (3)
* 6,264,659 Method of treating an intervertebral disk 142 1999
* 6,436,143 Method and apparatus for treating intervertebral disks 194 2000
RE43434 Method and apparatus for treating intervertebral disks 0 2004
 
WARSAW ORTHOPEDIC, INC. (7)
* 7,618,461 Composite intervertebral disc implants and methods for forming the same 20 2004
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7,520,900 Intervertebral disc nucleus implants and methods 17 2005
7,918,889 Expandable spinal prosthetic devices and associated methods 1 2006
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8,864,801 Method of deformity correction in a spine using injectable materials 0 2007
8,128,591 Multiple component mixing and delivery system 0 2008
 
CORE MEDICAL, INC. (1)
8,409,248 Plug with detachable guidewire element and methods for use 0 2010
 
SPINEOLOGY, INC. (6)
7,226,481 Expandable porous mesh bag device and methods of use for reduction, filling, fixation, and supporting of bone 104 2003
7,931,689 Method and apparatus for treating a vertebral body 20 2004
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7,959,683 Packed demineralized cancellous tissue forms for disc nucleus augmentation, restoration, or replacement and methods of implantation 13 2007
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CORDIS CORPORATION (12)
8,852,229 Locator and closure device and method of use 1 2003
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8,083,768 Vascular plug having composite construction 5 2005
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7,753,933 Plug with detachable guidewire element and methods for use 21 2005
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6,932,843 Apparatus and method for the in-situ formation of a structural prosthesis 53 2002
 
SPINEOVATIONS, INC. (3)
* 8,398,638 Method of treating spinal internal disk derangement 1 2005
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8,951,255 Method of treating spinal internal disk derangement 0 2013
 
DEPUY SYNTHES PRODUCTS, LLC (2)
8,556,949 Hybrid bone fixation element and methods of using the same 0 2008
8,357,199 Nucleus augmentation delivery device and technique 0 2012
 
GATEWAY MEDICAL, INC. (2)
6,736,815 Apparatus and methods for treating spinal discs 124 2001
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SPINEWAVE, INC. (1)
7,004,945 Devices and methods for the restoration of a spinal disc 83 2002
 
Pioneer Signal Technology, Inc. (1)
8,388,684 Artificial disc device 8 2003
 
DEPUY SYNTHES PRODUCTS, INC. (1)
8,197,545 Nucleus augmentation delivery device and technique 0 2005
 
SpineWave (1)
7,575,577 Devices and methods for the restoration of a spinal disc 28 2003
 
Anova Corporation (10)
* 6,352,557 Treating degenerative disc disease through transplantion of extracellular nucleus pulposus matrix and autograft nucleus pulposus cells 113 2000
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6,969,404 Annulus fibrosis augmentation methods and apparatus 116 2002
7,273,497 Methods for treating a defect in the annulus fibrosis 36 2003
* 2004/0186,573 Annulus fibrosis augmentation methods and apparatus 34 2004
9,084,616 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft 0 2006
7,914,553 Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft 10 2007
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8,936,642 Methods for treating a defect in the annulus fibrosis 0 2011
 
ZIMMER SPINE S.A.S. (2)
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GLOBUS MEDICAL, INC. (1)
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Endospine, Ltd. (1)
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ZIMMER ORTHOBIOLOGICS, INC. (1)
7,556,649 Methods and compositions for treating intervertebral disc degeneration 1 2004
 
JMEA Corporation (10)
7,632,313 Disc repair system 30 2005
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8,702,718 Implantation system for tissue repair 1 2007
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8,211,126 Tissue repair system 2 2009
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SPINE WAVE, INC. (7)
7,789,912 Apparatus and method for injecting fluent material at a distracted tissue site 11 2005
7,601,157 Devices and methods for the restoration of a spinal disc 24 2005
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CAUTHEN RESEARCH GROUP, INC. (1)
7,670,379 Spinal disc annulus reconstruction method 23 2006
 
MUSCULOSKELETAL TRANSPLANT FOUNDATION (1)
7,879,103 Vertebral disc repair 4 2006
* Cited By Examiner