Dipeptide apoptosis inhibitors and the use thereof
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United States of America Patent
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Feb 6, 2001
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N/A
app pub date -
Mar 16, 1999
filing date -
Oct 10, 1997
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Abstract
The present invention is directed to novel dipeptides thereof, represented by the general Formula I: ##STR1## where R.sub.1 -R.sub.3 and AA are defined herein. The present invention relates to the discovery that compounds having Formula I are potent inhibitors of apoptotic cell death. Therefore, the inhibitors of this invention can retard or block cell death in a variety of clinical conditions in which the loss of cells, tissues or entire organs occurs.
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