
US Patent No: 6,187,039
Number of patents in Portfolio can not be more than 2000
Tubular submucosal graft constructs
Stats
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Feb 13, 2001
Issued date -
May 4, 1999
filing date -
09/297,620
serial no -
In Force
status
Importance
Abstract
An easy-to-produce and mechanically strong tube of an implantable submucosal tissue has been developed which is manufactured in any desired length, wall thickness, or diameter. The construct produced by the method of the invention may be used as grafts for arteries, veins, ureters, urethras, shunts, or in any application where a compliant, tissue-compatible tube is needed. The manufacture of the submucosal tissue prosthesis generally involves wrapping a first sheet of submucosal tissue (60) and a second sheet of submucosal tissue (70) around a mandrel (50), wherein the first end (74) and the second opposite end (76) of the second sheet of submucosal tissue (70) are sutured together with sutures (78). The submucosal tissue is compressed and dried on the mandrel (50) before removing the construct by pulling on a first end (54) and a second end (56) of a water permeable tape to unwind the tape and thus release the construct for eventual use.
First Claim
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 5,693,085 Stent with collagen | 417 | 1995 | |
| 5,876,448 Esophageal stent | 197 | 1996 | |
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| 5,443,950 Three-dimensional cell and tissue culture system | 138 | 1993 | |
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| 5,922,028 Multi-layered SIS tissue graft construct for replacement of cartilaginous elements in situ | 88 | 1997 | |
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| 5,873,904 Silver implantable medical device | 657 | 1997 | |
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| 5,281,422 Graft for promoting autogenous tissue growth | 247 | 1991 | |
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