Oligonucleotide inhibition of epidermal growth factor receptor expression
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United States of America Patent
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Feb 13, 2001
Grant Date -
N/A
app pub date -
May 7, 1999
filing date -
Apr 4, 1997
priority date (Note) -
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Abstract
Compounds, compositions and methods are provided for inhibiting the expression of human EGFR. The compositions comprise oligonucleotides complementary to mRNA targeted to nucleic acids encoding EGFR. Methods of using these oligonucleotides for inhibition of EGFR expression and for treatment of diseases such as cancers associated with overexpression of EGFR are provided.
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