
US Patent No: 6,190,655
Number of patents in Portfolio can not be more than 2000
Methods of using Flt-3 ligand for exogenous gene transfer
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Feb 20, 2001
Issued date -
Sep 25, 1998
filing date -
09/160,841
serial no -
Expired
status
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Abstract
Ligands for flt3 receptors capable of transducing self-renewal signals to regulate the growth, proliferation or differentiation of progenitor cells and stem cells are disclosed. The invention is directed to flt3-L as an isolated protein, the DNA encoding the flt3-L, host cells transfected with cDNAs encoding flt3-L, compositions comprising flt3-L, methods of improving gene transfer to a mammal using flt3-L, and methods of improving transplantations using flt3-L. Flt3-L finds use in treating patients with anemia, AIDS and various cancers.
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First Claim
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 5,270,458 Nucleic acids encoding fragments of hematopoietic stem cell receptor flk-2 | 51 | 1992 | |
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