Polyketide derivatives and recombinant methods for making same
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United States of America Patent
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Mar 13, 2001
Grant Date -
N/A
app pub date -
Dec 23, 1997
filing date -
Jan 17, 1991
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention provides novel erythromycin derivatives in which methyl groups on the macrolactone ring have been substituted with --H, -Et, and/or --OH. The invention also provides reagents such as isolated polynucleotides, vectors comprising the polynucleotides and host cells transformed with the vectors for making the novel compounds. Methods for making the compounds utilizing genetic engineering techniques are also disclosed.
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