16-substituted-4-aza-androstane 5-.alpha.-reductase isozyme 1 inhibitors
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United States of America Patent
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Mar 20, 2001
Grant Date -
N/A
app pub date -
Jan 29, 1999
filing date -
Oct 21, 1993
priority date (Note) -
Expired
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Abstract
Compounds of the Formula I ##STR1## are inhibitors of the 5.alpha.-reductase 1 isozyme, and are useful alone, or in combination with a 5.alpha.-reductase 2 inhibitor, for the treatment of androgenic sensitive disorders such as acne vulgaris, seborrhea, female hirsutism, male pattern baldness, and benign prostatic hyperplasia.
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