Sentinel node identification using non-isotope means
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United States of America Patent
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Mar 20, 2001
Grant Date -
N/A
app pub date -
Nov 18, 1998
filing date -
Nov 19, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method for identifying a sentinel node is provided. The method includes injecting tumor-bearing tissue with a marking composition, radiating marking-agent-targeting energy into suspect tissues potentially harboring the sentinel node, and detecting a lymph node within the suspect tissues first infiltrated by the marking agent. The method is conducted without detecting radioactivity, and thus avoids the health and environmental problems posed by methods based on detecting radiolabels. Moreover, the method obviates the need for surgical dissection to initially detect potential sentinel nodes. Also provided are systems for performing the method and compositions for use in the method.
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