Ultrafine lightly coated superparamagnetic particles for MRI

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United States of America Patent

PATENT NO 6207134
SERIAL NO

09243437

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to particulate contrast agents, especially contrast agents for MR imaging having a metal oxide core which is preferably superparamagnetic iron oxide. The particulate contrast agents are provided with a low coating density of a polyelectrolyte coating agent selected from structural polysaccharides and synthetic polymers, especially polyaminoacids. Unlike conventional coated particulates, the new particles have reduced or no effect on cardiovascular parameters, platelet depletion, complement activation and blood coagulation.

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Patent Owner(s)

Patent OwnerAddress
GE HEALTHCARE ASOSLO

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fahlvik, Anne Kjersti Oslo, NO 11 190
Gundersen, Helge Oslo, NO 1 53
Jacobsen, Anne B.ae butted.rums Verk, NO 9 212
Klaveness, Jo Oslo, NO 187 4245
Nae, buttedvestad Anne Oslo, NO 4 383
Strande, Per Oslo, NO 29 767

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