Use of nucleic acids bound to carrier macromolecules
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United States of America Patent
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Mar 27, 2001
Grant Date -
N/A
app pub date -
May 18, 1999
filing date -
Nov 19, 1996
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Abstract
A nucleic acid primer is bound to a soluble carrier macromolecule, a multitude of primer molecules thus being carried by each carrier macromolecule, and hybridisation of the primer to a template followed by extension of the primer to replicate the template in complementary form is carried out as part of a PCR procedure or other amplification, or to form an extended primer of greater hybridization affinity. A second primer used in the amplification may also be bound to a carrier macromolecule.
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