Multivalent salts of pyridostigmine and related compounds
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United States of America Patent
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Apr 3, 2001
Grant Date -
N/A
app pub date -
Jun 29, 1999
filing date -
Nov 19, 1996
priority date (Note) -
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Abstract
A quaternary ammonium cholinergic agent is complexed with a multivalent anion, or with multiple monovalent anions. The complex may be administered orally to a patient to treat pain, or for some other purpose. Numerous modifications are contemplated, including modifications to the ring structure of the compound, substitution and functionalization of the ring. Other contemplated modifications include the use of different anions, including various monovalent and polyvalent anions, and both organic and inorganic anions. The compounds have utility as cholinergic agents, and especially in the treatment of mysasthenia gravis, chest pain, and carpal tunnel syndrome.
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