Optically active DNA probe having phosphonic diester linkage
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United States of America Patent
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Apr 3, 2001
Grant Date -
N/A
app pub date -
May 5, 1999
filing date -
May 6, 1998
priority date (Note) -
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Abstract
A DNA probe of the following structural formula (1) (wherein P* is an optically active phosphorus atom, each of R.sub.1 and R.sub.2 is a DNA oligomer having an arbitrary sequence, and R.sub.3 is a fluorescent intercalative dye attached via an appropriate linker) which has an optically active configuration about P*. ##STR1##
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