Copolymers of absorbable polyoxaesters
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United States of America Patent
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May 1, 2001
Grant Date -
N/A
app pub date -
Aug 11, 2000
filing date -
Mar 6, 1995
priority date (Note) -
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status (Latency Note)
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Abstract
The present invention describes a polyoxaester copolymer and blends thereof that may be used to produce hydrogels, surgical devices such as sutures, sutures with attached needles, molded devices, drug matrices, adhesives, sealants and the like. The invention also contemplates a process for producing these polyesters. The polyoxaester copolymers of the present invention are formed from a first divalent repeating unit of formula IA: [--O--C(O)--R.sub.30 --C(O)--] IA a second divalent repeating unit of the formula IB: [O--C(O)--C(R.sub.1)(R.sub.2)--O--R.sub.3 --O--C(R'.sub.1)(R'.sub.2)--C(O)--] IB and a third repeating unit selected from the group of formulas consisting of: [--O--R.sub.4 --].sub.A, II [--O--R.sub.5 --C(O)--].sub.B, III ([--O--R.sub.5 --C(O)].sub.P --O--).sub.L G XI and combinations thereof. These aliphatic polyoxaesters may be blended with other polymers that are preferably biocompatable.
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