Methods and compounds for tracking the biodistribution of macromolecule-carrier combinations

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United States of America Patent

PATENT NO 6225293
SERIAL NO

09145897

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Abstract

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The present invention provides improved methods for tracking the biodistribution of macromolecules and carriers in cells. In accordance with one embodiment, oligonucleotides and lipid carriers are differentially fluorescently labeled and coadministered to the cells. Useful compounds and synthetic methods are also provided.

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Patent Owner(s)

Patent OwnerAddress
ISIS PHARMACEUTICALS INC2280 FARADAY AVENUE CARLSBAD CA 92008 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, Clarence Frank Carlsbad, CA 18 687
Bhat, Balkrishen Carlsbad, CA 173 7460
Hebert, Normand Cardiff by the Sea, CA 20 1220
Manoharan, Muthiah Carlsbad, CA 491 18658

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