Use of alkylated iminosugars to treat multidrug resistance
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United States of America Patent
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May 1, 2001
Grant Date -
N/A
app pub date -
Nov 10, 1998
filing date -
Nov 10, 1997
priority date (Note) -
Expired
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Abstract
Methods and compositions for preventing, reducing, or reversing multidrug resistance (MDR) during cancer chemotherapy in patients undergoing treatment with therapeutically effective amounts of chemotherapeutic agents are provided. The methods comprise administering an anti-MDR effective amount of an N-substituted-1,5-dideoxy-1,5-imino-D-glucitol or galactitol iminosugar to a patient.
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