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Abstract

A novel psychophysical visual test based on the visual response of the eye to alternating chromatic complementary colors or achromatic grays of varying saturation, luminance and/or contrast is proposed for the early detection of glaucoma, and other diseases. In one embodiment, although the luminance level remains constant, the visual stimulus alternates between two complementary or counter phase colors, preferably against a gray background at about 40 times a sec, for example, between blue and yellow. When the colors are alternated in this manner, the visual stimulus appears white or gray to an observer, instead of either blue or yellow. As the saturation is reduced, however, the alternating colors appear grayer, and then eventually cannot be perceived. Persons suffering from glaucoma and other diseases, however, find it more difficult than normal people to distinguish the visual stimulus as the saturation and/or luminance is reduced. Observation thresholds for the visual stimulus can be measured by reducing the saturation of the alternating colors until the visual stimulus disappears against the gray background, and used beneficially to detect for the presence of glaucoma and other diseases. Alternatively, however, the luminance of the colors can be varied as the saturation is held constant, or varied together. In another embodiment, an achromatic stimulus consisting of black, white and grays may be used. In this latter instance, the visual stimulus consists of a circular patch or spot alternating preferably between black and white.

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First Claim