Non-radioactive hybridization assay and kit

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United States of America Patent

PATENT NO 6228578
SERIAL NO

08183154

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Abstract

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A non-radioactive hybridization assay and kit for the detection of genetic defects, microbial infections or viral infections, such as human papillomavirus. A test sample is treated with a base and incubated with nucleic acid probes, diluted in a neutralizing buffer, specific for target nucleic acids. The hybrids are captured onto a solid phase coated with an anti-hybrid antibody, unhybridized probe is eliminated, and the bound hybrid detected.

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Patent Owner(s)

  • DIGENE CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Challberg, Sharon Boyds, MD 3 79
Cullen, Allison Germantown, MD 2 66
Impraim, Chaka N. Potomac, MD 2 66
Lorincz, Attila Gaithersburg, MD 16 250

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