Polypeptides having thyrotropin-receptor activity, nucleic acid sequences coding for such receptors and polypeptides, and applications of these polypeptides
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United States of America Patent
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May 8, 2001
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N/A
app pub date -
Oct 15, 1991
filing date -
Dec 14, 1989
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Abstract
The invention concerns a polypeptide possessing thyrotropin receptor activity characterized in that it comprises the amino acid sequence shown in FIG. 11 (i.e., SEQ ID NO: 59) and cDNA molecules encoding this polypeptide. The invention also relates to vectors comprising cDNAs which encode the polypeptide of FIG. 11, cells transformed with these vectors, and the use the transformed cells expressing the thyrotropin receptor as in the detection of TSH or antibodies against the thyrotropin receptor.
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