Method of preventing abuse of opioid dosage forms
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United States of America Patent
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May 8, 2001
Grant Date -
N/A
app pub date -
Dec 22, 1998
filing date -
Dec 22, 1997
priority date (Note) -
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Abstract
The invention relates in part to a method of reducing the abuse potential of an oral dosage form of an opioid analgesic, wherein an analgesically effective amount of an orally active opioid agonist is combined with an opioid antagonist into an oral dosage form which would require at least a two-step extraction process to be separated from the opioid agonist, the amount of opioid antagonist including being sufficient to counteract opioid effects if extracted together with the opioid agonist and administered parenterally.
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