Nuclear receptor ligands and ligand binding domains

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United States of America Patent

PATENT NO 6236946
SERIAL NO

08764870

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides new methods, particularly computational methods, and compositions for the generation of nuclear receptor synthetic ligands based on the three dimensional structure of nuclear receptors, particularly the thyroid receptor (herein referred to as 'TR'). Also provided are crystals, nuclear receptor synthetic ligands, and related methods.

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Patent Owner(s)

  • REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Apriletti, James 11 Virginia Gardens, Berkeley, CA 94702 2 48
Baxter, John D 131 San Pablo Ave., San Francisco, CA 94127 21 218
Fletterick, Robert J 15 Christopher Ave., San Francisco, CA 94131 8 50
Kushner, Peter J 1362 6th Ave., San Francisco, CA 94122 21 115
Scanlan, Thomas S 2525 Moraga St., San Francisco, CA 94122 36 208
Shiau, Andrew K 34 Hugo St. #3, San Francisco, CA 94122 23 214
Wagner, Richard L 1704 Waller St., San Francisco, CA 94117 8 58
West, Brian 142 Anderson St., San Francisco, CA 94110 74 2399

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