Antisense oligonucleotide modulation of human mdm2 expression
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United States of America Patent
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May 29, 2001
Grant Date -
N/A
app pub date -
Mar 26, 1998
filing date -
Mar 26, 1998
priority date (Note) -
Expired
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Abstract
Compounds, compositions and methods are provided for inhibiting the expression of human mdm2. The compositions comprise antisense oligonucleotides targeted to nucleic acids encoding mdm2. Methods of using these oligonucleotides for inhibition of mdm2 expression and for treatment of diseases such as cancers associated with overexpression of mdm2 are provided.
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