Oxazolidinone combinatorial libraries, compositions and methods of preparation
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United States of America Patent
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May 29, 2001
Issued Date -
N/A
app pub date -
Jan 22, 1999
filing date -
Jan 23, 1998
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Expired
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Abstract
Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.
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