Antibodies for detecting p27 protein

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United States of America Patent

PATENT NO 6242575
SERIAL NO

08822936

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The subject invention provides an isolated protein having an apparent molecular weight of about 27 kD and capable of binding to and inhibiting the activation of a cyclin E-Cdk2 complex. The subject invention further provides an isolated antibody and a purified preparation of polyclonal and monoclonal antibodies which are specifically immunoreactive with a p27 protein. The subject invention further provides a kit for detecting a p27 protein.

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Patent Owner(s)

Patent OwnerAddress
GPC BIOTECH INC610 LINCOLN STREET WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Koff, Andrew New York, NY 14 221
Massague, Joan New York, NY 27 237
Polyak, Kornelia Baltimore, MD 25 205
Roberts, James M Seattle, WA 30 307

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