Phosphorothioate oligonucleotides having modified internucleoside linkages
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United States of America Patent
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Jun 5, 2001
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app pub date -
Jul 14, 1998
filing date -
Jul 14, 1998
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Abstract
Novel compounds that mimic and/or modulate the activity of wild-type nucleic acids. In general, the compounds are phosphorothioate oligonucleotides wherein the 5'-terminal internucleoside linkage or the 5'- and 3'-terminal linkages are modified.
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