Polynucleotide arrays and methods of making and using the same

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United States of America Patent

PATENT NO 6245518
SERIAL NO

09454822

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Abstract

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The present invention relates to methods of using labeled tracers to generate spatially addressable arrays of immobilized molecules, particularly polynucleotides, that can be normalized for differences in immobilization efficiencies at different addresses in the array. It also relates to the arrays generated by the method and to use of these arrays to enhance discrimination in array-based assays, particularly the discrimination between perfectly matched hybrids and hybrids containing a single mismatch in nucleic acid hybridization assays.

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Patent Owner(s)

Patent OwnerAddress
CALLIDA GENOMICS INC670 ALMANOR AVENUE SUNNYVALE CA 94085

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baier, Joerg Foster City, CA 8 161

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