Formulations and methods for treatment of mucosal associated conditions with an immune response modifier
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United States of America Patent
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Jun 12, 2001
Grant Date -
N/A
app pub date -
Jan 7, 2000
filing date -
Jan 8, 1999
priority date (Note) -
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Abstract
Immune response modifier (IRM) compounds--imidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, 1,2-bridged imidazoquinoline amines, thiazolo- and oxazolo-quinolinamines and pyridinamines, imidazonaphthyridine and tetrahydroimidazonaphthyridine amines--are useful for the treatment of conditions at and below the mucosal surfaces by administering a therapeutically effective amount of such compounds to the mucosal surface. Novel pharmaceutical formulations are provided. In one embodiment, the pharmaceutical formulations are advantageous for treatment of cervical conditions such as cervical dysplasias including cervical intraepithelial neoplasias.
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