Monoclonal antibodies that recognize antigens associated with tumor metastasis
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United States of America Patent
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Jun 12, 2001
Grant Date -
N/A
app pub date -
Jun 15, 1999
filing date -
Jun 15, 1998
priority date (Note) -
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Abstract
This invention provides tumor metastasis-inhibiting monoclonal antibodies, mAb 41-2, mAb 50-6 and mAb 1A-5. The antigen recognized by mAb 50-6 and mAb 1A-5 has been identified as the PETA-3 antigen. The antigen recognized by mAb 41-2 has been identified as a novel tumor metastasis-associated antigen. Compositions and methods are provided that are useful for treating and diagnosing metastatic tumors.
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