Antisense modulation of PKA catalytic subunit C-alpha expression

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United States of America Patent

PATENT NO 6248586
SERIAL NO

09467082

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Abstract

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Antisense compounds, compositions and methods are provided for modulating the expression of PKA catalytic subunit C-alpha. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PKA catalytic subunit C-alpha. Methods of using these compounds for modulation of PKA catalytic subunit C-alpha expression and for treatment of diseases associated with expression of PKA catalytic subunit C-alpha are provided.

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Patent Owner(s)

Patent OwnerAddress
ISIS PHARMACEUTICALS INC1896 RUTHERFORD ROAD CARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cowsert, Lex M Carlsbad, CA 219 3636
Monia, Brett P La Costa, CA 303 5836

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