Troponin I forms and use of the same

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United States of America Patent

PATENT NO 6248869
SERIAL NO

08865468

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Abstract

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The present invention relates to an isolated fragment of human cardiac troponin I (TnI) comprising the following sequence X-A-B-Y wherein X comprises any of amino acid residues 1-27 of SEQ ID NO: 2; A comprises amino acid residues 28-69 of SEQ ID NO: 2; B comprises amino acid residues 70-90 of SEQ ID NO: 2; and Y comprises any of amino acid residues 91-170 of SEQ ID NO: 2. The present invention further relates to fragments of TnI wherein the fragment has a greater immunologic reactivity than intact cTnI when the fragment and intact cTnI are reacted with a monoclonal antibody, which has an epitopic site on the fragment.

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Patent Owner(s)

Patent OwnerAddress
MEDICAL ANALYSIS SYSTEMS INC542 FLYNN ROAD CAMARILLO CA 93012

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Morjana, Nihmat A Pembroke Pines, FL 1 6
Puia, Angela M Miami, FL 1 6

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