Methods and assay kits for detecting altered mononuclear cell phenotype related to a pro-tumor immune response
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United States of America Patent
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Jun 26, 2001
Grant Date -
N/A
app pub date -
Nov 5, 1999
filing date -
Jan 14, 1999
priority date (Note) -
Expired
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Abstract
A method for screening for a pro-tumor immune response according to the present invention, the method comprises: contacting a clinical sample with one or more detector molecules for detecting, and then determining the amount of, mononuclear cell phenotype in the sample; and (b) comparing the amount of mononuclear cell phenotype determined in the sample to a reference value for the mononuclear cell phenotype; wherein a significant difference in the amount of mononuclear cell phenotype determined as compared to the reference value may be an indicator of the presence of a pro-tumor immune response. Also provided are assay kits for determining an amount of mononuclear cell phenotype in performing the methods according to the present invention.
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