Targeted immunostimulation with bispecific reagents
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United States of America Patent
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Jul 10, 2001
Grant Date -
N/A
app pub date -
May 30, 1995
filing date -
Oct 5, 1990
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Disclosed are methods of stimulating in a subject an immune response to an antigen to which the immune response is targeted. This method includes the step of administering to the subject a binding agent which binds a surface receptor of an antigen-presenting cell, in some instances without being blocked substantially by the natural ligand for the surface receptor, and an antigen to which the immune response is targeted, in a physiologically acceptable medium to the subject. Also disclosed are molecular complexes including the binding agent coupled to an antigen.
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