Method for making biocompatible medical article

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United States of America Patent

PATENT NO 6258371
SERIAL NO

09054389

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for making a biocompatible medical article, and preferably, a blood compatible medical article, through the use of a copolymer coating. The copolymer coating is synthesized using methacrylate or acrylate monomers with a functional group (primary amino group) for subsequent attachment of heparin. Synthesis of the copolymer coating is carried out using the proper proportion of hydrophobic monomer/hydrophilic monomer/functional monomer in order to optimize the solubility of the copolymer in alcohol, its insolubility in water (before and after heparin coupling), the heparin coupling efficacy and heparin bioactivity. Once the copolymer coating is fashioned, a medical article is coated with it. The coating is thereafter dried and heparin attached. In such a manner the present invention provides for a method for making a biocompatible medical article, and preferably, a blood compatible medical article.

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Patent Owner(s)

Patent OwnerAddress
JARO MICHAEL JMEDTRONIC INC MS 301 7000 CENTRAL AVENUE NE MINNEAPOLIS MN 55432

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cahalan, Patrick Geleen, NL 30 1748
Fogt, Eric Maple Grove, MN 3 437
Ishihara, Kazuhiko Tokyo, JP 66 1032
Koulik, Edouard Maastricht, NL 9 1166
Nakabayashi, Nobuo Chiba-Ken, JP 32 1152
Vincent, Larik Landgraaf, NL 2 417

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