Retro-, inverso- and retro-inverso synthetic peptide analogues
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United States of America Patent
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Jul 17, 2001
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N/A
app pub date -
Aug 12, 1997
filing date -
Aug 27, 1992
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Abstract
Synthetic peptide antigen analogues of native peptide antigens with partial or complete retro, inverso or retro-inverso modifications are provided. When administered as an immunogen to an immunocompetent host the synthetic peptide antigen analogues induce the production of antibodies which recognize the native peptide antigen. Uses of these analogues, vaccines and methods of preparing vaccines comprising these antigen analogues, and antibodies generated using these antigen analogues are also provided.
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