Method for preparing oxycodone
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United States of America Patent
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Jul 17, 2001
Grant Date -
N/A
app pub date -
Sep 22, 2000
filing date -
Oct 15, 1999
priority date (Note) -
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Abstract
A method for the preparation of oxycodone, and salts thereof, from codeine comprising oxidation of codeine to codeinone, formation of an dienolsilyl ether congener of codeinone in strong amine base, oxidation of the dienolsilyl ether congener using peracetic acid, and hydrogenation of the resulting 14-hydroxycodeinone product.
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