Clear oil-containing pharmaceutical compositions
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United States of America Patent
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Jul 31, 2001
Grant Date -
N/A
app pub date -
Jun 30, 1999
filing date -
Jun 30, 1999
priority date (Note) -
In Force
status (Latency Note)
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Abstract
The present invention relates to pharmaceutical compositions and methods for improved solubilization of triglycerides and improved delivery of therapeutic agents. Compositions of the present invention include a triglyceride and a carrier, where the carrier is formed from a combination of at least two surfactants, at least one of which is hydrophilic. Upon dilution with an aqueous solvent, the composition forms a clear, aqueous dispersion of the triglyceride and surfactants. An optional therapeutic agent can be incorporated into the composition, or can be co-administered with the composition. The invention also provides methods of enhancing triglyceride solubility and methods of treatment with therapeutic agents using these compositions.
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