Analytical methods and materials for nucleic acid detection
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United States of America Patent
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Jul 31, 2001
Grant Date -
N/A
app pub date -
Nov 22, 1999
filing date -
Mar 13, 1998
priority date (Note) -
Expired
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Abstract
Mass spectrometric, absorbance spectroscopic and fluorescence spectroscopic processes are disclosed to detect the depolymerization of a nucleic acid hybrid in order to qualitatively and quantitatively assay for the presence of a predetermined nucleic acid target. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like, including multiplexed assays.
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