Collagenase-1 and stromelysin-1 inhibitors, pharmaceutical compositions comprising same and methods of their use
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United States of America Patent
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Aug 7, 2001
Grant Date -
N/A
app pub date -
Jul 9, 1999
filing date -
Jun 18, 1996
priority date (Note) -
Expired
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Abstract
Novel inhibitors of metalloproteases, in particular collagenase-1 and stromelysin-1, are disclosed. Such compounds are useful in pharmaceutical compositions and methods for treating or controlling disease states or conditions which involve tissue breakdown, such as rheumatoid arthritis.
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