Carbohydrate or 2'-modified oligonucleotides having alternating internucleoside linkages
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United States of America Patent
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Aug 21, 2001
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app pub date -
Jul 14, 1998
filing date -
Jul 14, 1998
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Abstract
Noel compounds that mimic and/or modulate the activity of wild-type nucleic acids. In general, the compounds are oligonucleotides which contain at least one region of 2'-modified nucleosides connected by alternating phosphodiester and phosphorothioate linkages.
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