US Patent No: 6,278,894

Number of patents in Portfolio can not be more than 2000

Multi-site impedance sensor using coronary sinus/vein electrodes

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method and apparatus for performing impedance plethysmography on a living heart for diagnostic and therapy purposes involves placement of plural leads where at least one is disposed within a coronary vein traversing the myocardium on the left side of the heart with another lead having plural electrodes thereon disposed in the right ventricle. By appropriate selection of electrodes on the first and second leads for driving with an AC carrier signal and other such electrodes coupled to a sensing amplifier, an impedance vs. time signal can be derived that when signal processed provides useful information concerning cardiac performance. The multi-site impedance sensing has been found to yield more robust data especially in patients having CHF.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
CARDIAC PACEMAKERS, INC.ST PAUL, MN2957

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kadhiresan, V A Lino Lakes, MN 5 795
Nugent, Kevin G Minneapolis, MN 3 700
Salo, Rodney W Fridley, MN 116 6715

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Cardiac Pacemakers, Inc. (6)
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5,190,035 Biomedical method and apparatus for controlling the administration of therapy to a patient in response to changes in physiological demand 195 1986
5,036,849 Variable rate cardiac pacer 140 1990
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MEDTRONIC, INC. (2)
5,501,702 Time sharing multipolar rheography apparatus and method 96 1994
* 5,836,976 Cardioversion energy reduction system 134 1997
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
KONINKLIJKE PHILIPS ELECTRONICS N.V. (1)
* 6,625,487 Bioelectrical impedance ECG measurement and defibrillator implementing same 19 2001
 
Other [Check patent profile for assignment information] (7)
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9,415,226 Method and apparatus with anodal capture monitoring 0 2007
* 2010/0056,884 THORACIC OR INTRACARDIAC IMPEDANCE DETECTION WITH AUTOMATIC VECTOR SELECTION 3 2009
* 2011/0009,767 METHOD AND APPARATUS FOR TRENDING A PHYSIOLOGICAL CARDIAC PARAMETER 1 2010
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* 2011/0137,363 METHOD AND APPARATUS FOR INITIATING AND DELIVERING CARDIAC PROTECTION PACING 8 2011
9,421,390 Methods and devices implementing dual criteria for arrhythmia detection 0 2015
 
ST. JUDE MEDICAL AB (4)
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8,718,767 Cardiac stimulating device 0 2009
 
ELECTROHEALING HOLDINGS, INC. (1)
6,731,979 Pulse width cardiac pacing apparatus 96 2001
 
REGENTS OF THE UNIVERSITY OF MINNESOTA (8)
7,313,434 Impedance monitoring for detecting pulmonary edema and thoracic congestion 13 2002
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7,184,821 Monitoring thoracic fluid changes 49 2003
* 2005/0124,908 Monitoring thoracic fluid changes 35 2003
7,447,543 Pathology assessment with impedance measurements using convergent bioelectric lead fields 7 2005
* 2006/0184,060 Pathology assessment with impedance measurements using convergent bioelectric lead fields 33 2005
8,131,356 Impedance monitoring for detecting pulmonary edema and thoracic congestion 0 2007
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RHYTHMIA MEDICAL, INC. (39)
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8,538,509 Intracardiac tracking system 5 2008
* 2009/0253,976 Intracardiac Tracking System 53 2008
* 2008/0249,424 Non-Contact Cardiac Mapping, Including Moving Catheter and Multi-Beat Integration 22 2008
8,167,876 Tracking system using field mapping 0 2008
8,137,343 Tracking system using field mapping 12 2008
7,953,475 Preprocessing for cardiac mapping 25 2009
7,930,018 Cardiac mapping, including moving catheter and multi-beat integration 37 2009
* 2009/0177,071 Non-Contact Cardiac Mapping, Including Preprocessing 33 2009
* 2009/0177,072 Non-Contact Cardiac Mapping, Including Moving Catheter and Multi-Beat Integration 45 2009
9,398,862 Multi-electrode mapping system 0 2009
* 2010/0274,150 Multi-Electrode Mapping System 0 2009
8,571,647 Impedance based anatomy generation 0 2009
8,103,338 Impedance based anatomy generation 12 2009
* 2010/0286,551 Impedance Based Anatomy Generation 20 2009
* 2010/0286,550 Impedance Based Anatomy Generation 7 2009
7,937,136 Cardiac mapping, including resolution map 12 2009
9,131,869 Tracking using field mapping 0 2010
8,694,074 Electrode displacement determination 0 2010
7,957,792 Spatial resolution determination for cardiac mapping 13 2010
* 2010/0305,433 NON-CONTACT CARDIAC MAPPING, INCLUDING RESOLUTION MAP 4 2010
8,615,287 Catheter tracking and endocardium representation generation 0 2010
8,948,853 Cardiac mapping with catheter shape information 0 2011
8,433,394 Cardiac mapping 2 2011
* 2011/0190,625 CARDIAC MAPPING 4 2011
* 2011/0160,574 CARDIAC MAPPING WITH CATHETER SHAPE INFORMATION 0 2011
8,401,625 Multi-electrode mapping system 0 2011
9,002,442 Beat alignment and selection for cardiac mapping 0 2011
9,113,809 Impedance based anatomy generation 0 2012
8,568,406 Tracking system using field mapping 1 2012
8,463,368 Intra-cardiac tracking system 2 2012
8,744,566 Impedance based anatomy generation 0 2012
8,942,786 Tracking using field mapping 1 2012
8,989,851 Cardiac mapping 0 2013
8,725,240 Intracardiac tracking system 0 2013
9,014,793 Intracardiac tracking system 0 2014
9,289,148 Electroanatomical mapping 0 2014
 
BIOPHAN TECHNOLOGIES, INC. (19)
6,968,236 Ceramic cardiac electrodes 19 2002
7,013,174 Electromagnetic interference immune tissue invasive system 23 2002
7,010,357 Electromagnetic interference immune tissue invasive system 21 2002
6,850,805 Electromagnetic interference immune tissue invasive system 31 2002
6,845,266 Electromagnetic interference immune tissue invasive system 25 2002
6,819,958 Electromagnetic interference immune tissue invasive system 63 2002
6,799,069 Electromagnetic interference immune tissue invasive system 66 2002
6,795,736 Electromagnetic interference immune tissue invasive system 49 2002
6,778,856 Electromagnetic interference immune tissue invasive system 52 2002
6,763,268 Electromagnetic interference immune tissue invasive system 48 2002
6,760,628 Electromagnetic interference immune tissue invasive system 62 2002
6,757,566 Electromagnetic interference immune tissue invasive system 45 2002
6,718,203 Electromagnetic interference immune tissue invasive system 70 2002
6,718,207 Electromagnetic interference immune tissue invasive system 66 2002
6,711,440 MRI-compatible medical device with passive generation of optical sensing signals 180 2002
6,725,092 Electromagnetic radiation immune medical assist device adapter 84 2002
7,054,686 Pulsewidth electrical stimulation 61 2002
6,988,001 Hermetic component housing for photonic catheter 25 2002
7,389,137 Optical MRI catheter system 5 2005
 
Rhythmin Medical, Inc. (1)
7,957,791 Multi-beat integration for cardiac mapping 14 2008
 
Biopham Technologies Inc. (1)
6,980,848 Optical MRI catheter system 5 2005
 
CAMERON HEALTH, INC. (59)
* 6,721,597 Subcutaneous only implantable cardioverter defibrillator and optional pacer 176 2000
7,076,294 Method of implanting ICD and subcutaneous lead 29 2004
7,302,300 Subcutaneous electrode for transthoracic conduction with highly maneuverable insertion tool 1 2004
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7,239,925 Subcutaneous electrode for transthoracic conduction with improved installation characteristics 2 2004
7,299,092 Subcutaneous electrode for transthoracic conduction with low profile installation appendage 3 2004
7,299,097 Subcutaneous electrode for transthoracic conduction with insertion tool 3 2004
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7,274,962 Subcutaneous electrode with improved contact shape for transthoracic conduction 7 2004
7,330,757 Method for discriminating between ventricular and supraventricular arrhythmias 52 2004
7,248,921 Method and devices for performing cardiac waveform appraisal 66 2004
7,379,772 Apparatus and method of arrhythmia detection in a subcutaneous implantable cardioverter/defibrillator 29 2004
* 2004/0236,379 Apparatus and method of arrhythmia detection in a subcutaneous implantable cardioverter/defibrillator 12 2004
7,120,496 Radian curve shaped implantable cardioverter-defibrillator canister 11 2004
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7,392,085 Multiple electrode vectors for implantable cardiac treatment devices 28 2004
7,536,222 Nonvascular implantable defibrillator and method 7 2004
7,181,274 Methods for inducing fibrillation utilizing subcutaneous electrodes 12 2004
* 2005/0137,625 Power supply for a subcutaneous implantable cardioverter-defibrillator 1 2004
7,477,935 Method and apparatus for beat alignment and comparison 27 2004
7,376,458 Method for defining signal templates in implantable cardiac devices 30 2004
* 2006/0116,725 Method and apparatus for beat alignment and comparison 10 2004
7,655,014 Apparatus and method for subcutaneous electrode insertion 37 2004
8,229,563 Devices for adapting charge initiation for an implantable cardioverter-defibrillator 5 2005
8,160,697 Method for adapting charge initiation for an implantable cardioverter-defibrillator 4 2005
7,555,338 Methods and implantable devices for inducing fibrillation by alternating constant current 1 2005
7,627,367 Multiple electrode vectors for implantable cardiac treatment devices 12 2005
7,444,182 Method for discriminating between ventricular and supraventricular arrhythmias 28 2005
7,623,920 Low power A/D converter 0 2005
8,116,867 Methods and devices for tachyarrhythmia sensing and high-pass filter bypass 1 2005
7,428,437 Canister designs for implantable cardioverter-defibrillators 5 2005
* 2006/0004,416 Canister designs for implantable cardioverter-defibrillators 1 2005
7,813,797 Cardioverter-defibrillator having a focused shocking area and orientation thereof 19 2006
8,788,023 Systems and methods for sensing vector selection in an implantable medical device 3 2006
7,623,909 Implantable medical devices and programmers adapted for sensing vector selection 7 2006
7,657,311 Subcutaneous only implantable cardioverter-defibrillator and optional pacer 19 2006
7,627,375 Implantable cardiac stimulus methods 18 2006
8,718,793 Electrode insertion tools, lead assemblies, kits and methods for placement of cardiac device electrodes 2 2006
7,623,913 Implantable medical devices using heuristic filtering in cardiac event detection 29 2006
7,877,139 Method and device for implantable cardiac stimulus device lead impedance measurement 3 2006
8,014,851 Signal analysis in implantable cardiac treatment devices 2 2006
7,720,534 Transthoracic impedance measurement in a subcutaneous device 20 2006
9,144,683 Post-shock treatment in a subcutaneous device 0 2006
7,623,916 Implantable cardiac stimulus devices and methods with input recharge circuitry 28 2006
7,783,340 Systems and methods for sensing vector selection in an implantable medical device using a polynomial approach 6 2007
8,200,341 Sensing vector selection in a cardiac stimulus device with postural assessment 6 2007
8,447,398 Subcutaneous implantable cardioverter-defibrillator placement methods 3 2007
7,991,459 Method for defining signal templates in implantable cardiac devices 3 2007
8,942,802 Method for discriminating between ventricular and supraventricular arrhythmias 0 2008
8,160,699 Cardioverter-defibrillator having a focused shocking area and orientation thereof 3 2010
8,626,285 Method and devices for performing cardiac waveform appraisal 1 2012
8,781,602 Sensing vector selection in a cardiac stimulus device with postural assessment 1 2013
9,149,645 Methods and devices implementing dual criteria for arrhythmia detection 0 2014
9,216,284 Electrode insertion tools, lead assemblies, kits and methods for placement of cardiac device electrodes 0 2014
9,138,589 Apparatus and method for identifying atrial arrhythmia by far-field sensing 0 2014
9,364,677 Systems and methods for sensing vector selection in an implantable medical device 0 2014
8,965,530 Implantable cardiac devices and methods using an x/y counter 0 2014
9,155,485 Method for discriminating between ventricular and supraventricular arrhythmias 0 2014
9,357,969 Sensing vector selection in a cardiac stimulus device with postural assessment 0 2015
 
MEDTRONIC, INC. (18)
7,047,074 Electromagnetic interference immune tissue invasive system 41 2002
6,993,387 Electromagnetic interference immune tissue invasive system 23 2002
6,954,674 Electromagnetic interference immune tissue invasive system 42 2002
6,901,290 Electromagnetic interference immune tissue invasive system 41 2002
6,829,509 Electromagnetic interference immune tissue invasive system 56 2002
6,819,954 Electromagnetic interference immune tissue invasive system 35 2002
7,610,088 Method and apparatus for assessing left ventricular function and optimizing cardiac pacing intervals based on left ventricular wall motion 11 2003
* 2004/0172,078 Method and apparatus for assessing left ventricular function and optimizing cardiac pacing intervals based on left ventricular wall motion 23 2003
7,142,919 Reconfigurable, fault tolerant multiple-electrode cardiac lead systems 47 2003
* 2005/0090,870 Reconfigurable, fault tolerant multiple-electrode cardiac lead systems 16 2003
7,225,035 Multipolar medical electrical lead 32 2004
8,527,046 MRI-compatible implantable device 0 2004
7,450,996 Medical device with an electrically conductive anti-antenna geometrical shaped member 20 2004
* 2006/0235,289 Pacemaker lead with motion sensor 55 2005
7,937,150 Lead-carried proximal electrode for quadripolar transthoracic impedance monitoring 0 2006
* 2007/0179,544 Lead-carried proximal electrode for quadripolar transthoracic impedance monitoring 0 2006
8,150,513 Method and apparatus for assessing left ventricular function and optimizing cardiac pacing intervals based on left ventricular wall motion 8 2009
8,521,286 Lead-carried proximal electrode for quadripolar transthoracic impedance monitoring 0 2011
 
GE MEDICAL SYSTEMS INFORMATION TECHNOLOGIES, INC. (2)
* 6,974,420 Method and apparatus for reducing noise and detecting electrode faults in medical equipment 2 2002
* 2002/0183,797 Method and apparatus for reducing noise and detecting electrode faults in medical equipment 1 2002
 
Cardiac Pacemakers, Inc. (130)
7,340,303 Evoked response sensing for ischemia detection 30 2001
7,127,289 Cardiac resynchronization system employing mechanical measurement of cardiac walls 16 2001
* 2003/0105,496 Cardiac resynchronization system employing mechanical measurement of cardiac walls 44 2001
6,892,095 Method and apparatus for monitoring left ventricular work or power 64 2001
* 2003/0125,774 Method and apparatus for monitoring left ventricular work or power 13 2001
7,236,821 Chronically-implanted device for sensing and therapy 173 2002
* 2003/0158,584 Chronically-implanted device for sensing and therapy 157 2002
6,957,105 Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals 6 2002
* 2003/0187,482 Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals 3 2002
7,113,825 Method and apparatus for detecting acoustic oscillations in cardiac rhythm 49 2002
* 2003/0208,240 Method and apparatus for detecting acoustic oscillations in cardiac rhythm 22 2002
7,039,462 Method and apparatus for detecting oscillations in cardiac rhythm 83 2002
* 2003/0233,132 Method and apparatus for detecting oscillations in cardiac rhythm 15 2002
7,089,055 Method and apparatus for delivering pre-shock defibrillation therapy 16 2002
6,965,797 Method and apparatus for assessing and treating myocardial wall stress 51 2002
* 2004/0054,381 Method and apparatus for assessing and treating myocardial wall stress 18 2002
7,072,711 Implantable device for delivering cardiac drug therapy 52 2002
7,065,405 Stress reduction pacing mode for arrhythmia prevention 29 2002
* 2004/0098,057 Stress reduction pacing mode for arrhythmia prevention 13 2002
7,972,275 Method and apparatus for monitoring of diastolic hemodynamics 9 2002
7,369,890 Technique for discriminating between coordinated and uncoordinated cardiac rhythms 15 2003
7,171,258 Method and apparatus for trending a physiological cardiac parameter 37 2003
7,320,675 Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure 25 2003
8,050,764 Cross-checking of transthoracic impedance and acceleration signals 7 2003
* 2005/0096,704 Cross-checking of transthoracic impedence and acceleration signals 11 2003
7,627,373 Method and apparatus for cell and electrical therapy of living tissue 6 2003
* 7,272,442 Automatically configurable minute ventilation sensor 7 2003
* 2004/0186,526 Automatically configurable minute ventilation sensor 3 2003
7,425,210 Drug delivery system for implantable medical device 5 2003
8,271,093 Systems and methods for deriving relative physiologic measurements using a backend computing system 11 2004
7,346,394 Cardiac stimulation at high ventricular wall stress areas 21 2004
* 2005/0065,568 Cardiac stimulation at high ventricular wall stress areas 10 2004
7,206,637 Cardiac pacing using sensed coronary vein blood temperature and left ventricular flow rate 32 2004
8,060,219 Epicardial patch including isolated extracellular matrix with pacing electrodes 3 2004
7,981,065 Lead electrode incorporating extracellular matrix 2 2004
7,917,210 Method and apparatus for cardiac protection pacing 15 2005
* 2006/0259,087 Method and apparatus for cardiac protection pacing 61 2005
7,376,463 Therapy control based on the rate of change of intracardiac impedance 22 2005
* 2007/0005,114 Therapy control based on the rate of change of intracardiac impedance 6 2005
7,257,443 Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals 31 2005
* 2005/0256,542 Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals 3 2005
8,494,618 Intracardiac impedance and its applications 0 2005
* 2007/0043,394 Intracardiac impedance and its applications 35 2005
7,742,815 Using implanted sensors for feedback control of implanted medical devices 9 2005
7,974,691 Method and apparatus for controlling cardiac resynchronization therapy using cardiac impedance 3 2005
* 2007/0066,905 Method and apparatus for controlling cardiac resynchronization therapy using cardiac impedance 17 2005
7,440,803 Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods 13 2005
8,108,034 Systems and methods for valvular regurgitation detection 13 2005
7,580,746 Implantable medical device for generating cardiac pressure-volume loop and optimizing therapy 35 2005
* 2007/0129,765 Implantable medical device for generating cardiac pressure-volume loop and optimizing therapy 38 2005
7,844,331 Method and apparatus for controlling anti-tachyarrhythmia pacing using hemodynamic sensor 5 2005
* 2007/0142,866 Method and apparatus for controlling anti-tachyarrhythmia pacing using hemodynamic sensor 26 2005
7,894,896 Method and apparatus for initiating and delivering cardiac protection pacing 5 2006
* 2006/0287,684 METHOD AND APPARATUS FOR INITIATING AND DELIVERING CARDIAC PROTECTION PACING 69 2006
8,275,456 Implantable device for delivering cardiac drug therapy 0 2006
8,000,780 Detection of myocardial ischemia from the time sequence of implanted sensor measurements 6 2006
7,826,891 Method and apparatus for trending a physiological cardiac parameter 1 2006
* 2007/0049,835 METHOD AND APPARATUS FOR TRENDING A PHYSIOLOGICAL CARDIAC PARAMETER 28 2006
7,904,155 Cardiac resynchronization method and apparatus employing mechanical measurement of cardiac walls 4 2006
* 2007/0129,781 CARDIAC RESYNCHRONIZATION SYSTEM EMPLOYING MECHANICAL MEASUREMENT OF CARDIAC WALLS 6 2006
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* 2008/0097,539 METHOD AND APPARATUS FOR DETECTING FIBRILLATION USING CARDIAC LOCAL IMPEDANCE 35 2006
7,738,967 Cardiac pacing using sensed coronary vein blood temperature and left ventricular flow rate 17 2007
* 2007/0112,388 Cardiac pacing using sensed coronary vein blood temperature and left ventricular flow rate 55 2007
8,306,621 Cardiac cycle synchronized sampling of impedance signal 5 2007
8,615,296 Method and apparatus for closed-loop intermittent cardiac stress augmentation pacing 1 2007
7,840,267 Closed-loop resynchronization therapy for mechanical dyssynchrony 0 2007
7,890,167 Pain free defibrillation threshold estimation 2 2007
* 2008/0249,581 PAIN FREE DEFIBRILLATION THRESHOLD ESTIMATION 4 2007
7,930,022 System and method to determine hemodynamic tolerability 1 2007
* 2008/0281,367 SYSTEM AND METHOD TO DETERMINE HEMODYNAMIC TOLERABILITY 10 2007
8,070,686 Monitoring lung fluid status using the cardiac component of a thoracic impedance-indicating signal 0 2007
* 2009/0012,416 MONITORING LUNG FLUID STATUS USING THE CARDIAC COMPONENT OF A THORACIC IMPEDANCE-INDICATING SIGNAL 14 2007
7,955,268 Multiple sensor deployment 0 2007
7,881,789 Method and apparatus for detecting oscillations in cardiac rhythm with electrogram signals 0 2007
8,209,011 Automatically configurable minute ventilation sensor 1 2007
7,979,123 Intermittent stress augmentation pacing for cardioprotective effect 9 2007
8,016,783 Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure 7 2007
8,126,548 Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods 2 2008
* 2008/0114,410 CLOSED LOOP IMPEDANCE-BASED CARDIAC RESYNCHRONIZATION THERAPY SYSTEMS, DEVICES, AND METHODS 13 2008
7,725,185 Cardiac stimulation at high ventricular wall stress areas 6 2008
7,953,485 Therapy control based on the rate of change of intracardiac impedance 0 2008
* 2008/0249,583 THERAPY CONTROL BASED ON THE RATE OF CHANGE OF INTRACARDIAC IMPEDANCE 16 2008
8,295,927 Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods 1 2008
* 2009/0149,766 CORONARY VEIN HEMODYNAMIC SENSOR 3 2008
8,725,260 Methods of monitoring hemodynamic status for rhythm discrimination within the heart 0 2009
8,369,960 Systems and methods for controlling wireless signal transfers between ultrasound-enabled medical devices 0 2009
7,899,532 Method and apparatus for minimizing post-infarct ventricular remodeling 1 2009
8,818,507 Coronary vein dimensional sensor and fixation apparatus 0 2009
* 2009/0299,427 CORONARY VEIN DIMENSIONAL SENSOR AND FIXATION APPARATUS 0 2009
8,509,892 Method and apparatus for controlling anti-tachyarrhythmia therapy using hemodynamic tolerability 0 2009
8,034,000 Ischemia detection using a heart sound sensor 6 2009
8,591,423 Systems and methods for determining cardiac output using pulmonary artery pressure measurements 0 2009
8,632,470 Assessment of pulmonary vascular resistance via pulmonary artery pressure 0 2009
8,014,860 Thoracic or intracardiac impedance detection with automatic vector selection 4 2009
8,036,744 Cardiac rhythm management system with defibrillation threshold prediction 1 2009
8,412,326 Pacemaker with vagal surge monitoring and response 1 2010
8,983,600 Method and apparatus for safety control during cardiac pacing mode transition 0 2010
8,958,873 Method and apparatus for safe and efficient delivery of cardiac stress augmentation pacing 0 2010
7,949,394 Using implanted sensors for feedback control of implanted medical devices 2 2010
* 2010/0305,635 SYSTEM AND METHOD FOR RHYTHM IDENTIFICATION AND THERAPY DISCRIMINATION USING HEMODYNAMIC STATUS INFORMATION 4 2010
8,423,140 System and method for decompensation detection and treatment based on patient hemodynamics 2 2010
8,417,336 System and method for pacing rate control utilizing patient hemodynamic status information 1 2010
* 2010/0305,650 SYSTEM AND METHOD FOR PACING RATE CONTROL UTILIZING PATIENT HEMODYNAMIC STATUS INFORMATION 2 2010
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7,938,781 Hemodynamic stability assessment based on heart sounds 11 2010
8,812,104 Method and apparatus for automated control of pacing post-conditioning 0 2010
8,340,747 Method and apparatus for trending a physiological cardiac parameter 1 2010
8,929,990 Transvascular neural stimulation device and method for treating hypertension 0 2010
8,792,980 Cardiac resynchronization system employing mechanical measurement of cardiac walls 0 2010
8,636,669 Method and apparatus for monitoring of diastolic hemodynamics 2 2011
8,768,460 Pain free defibrillation threshold estimation 0 2011
8,396,552 Method and apparatus for initiating and delivering cardiac protection pacing 2 2011
8,340,764 Method and apparatus for cardiac protection pacing 2 2011
8,612,001 Method and apparatus for minimizing post-infarct ventricular remodeling 0 2011
8,712,521 Method and apparatus for controlling cardiac resynchronization therapy using cardiac impedance 0 2011
8,473,050 Thoracic or intracardiac impedance detection with automatic vector selection 1 2011
8,758,260 Ischemia detection using a heart sound sensor 0 2011
8,423,142 Cross-checking of transthoracic impedance and acceleration signals 3 2011
9,295,405 SV/CO trending via intracardiac impedance 0 2012
8,852,099 Systems and methods for deriving relative physiologic measurements 1 2012
8,442,633 Cardiac cycle synchronized sampling of impedance signal 2 2012
8,660,648 Implantable and rechargeable neural stimulator 1 2012
8,594,789 Method and apparatus for trending a physiological cardiac parameter 1 2012
8,855,762 Method and apparatus for cardiac protection pacing 2 2012
* 8,583,232 System and method for pacing rate control utilizing patient hemodynamic status information 1 2013
8,825,156 System and method for decompensation detection and treatment based on patient hemodynamics 0 2013
8,688,214 Cardiac cycle synchronized sampling of impedance signal 0 2013
8,761,876 Thoracic or intracardiac impedance detection with automatic vector selection 0 2013
8,880,171 Cardiac cycle synchronized sampling of impedance signal 0 2014
 
BIOPAN TECHNOLOGIES, INC. (1)
6,925,328 MRI-compatible implantable device 144 2001
 
CASE WESTERN RESERVE UNIVERSITY (2)
* 7,016,719 System and methods for noninvasive electrocardiographic imaging (ECGI) using generalized minimum residual (GMRes) 80 2002
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REMON MEDICAL TECHNOLOGIES LTD. (4)
7,621,905 Devices for intrabody delivery of molecules and systems and methods utilizing same 19 2003
7,813,808 Implanted sensor system with optimized operational and sensing parameters 1 2005
7,641,619 Barometric pressure correction based on remote sources of information 23 2007
7,948,148 Piezoelectric transducer 4 2009
 
BIOTRONIK GMBH & CO. KG (2)
7,330,759 Biventricular cardiac pacemaker for cardiac resynchronisation therapy 4 2003
* 2006/0142,811 Biventricular cardiac pacemaker for cardiac resynchronisation therapy 2 2003
 
Pacesetter, Inc. (23)
* 2002/0002,389 Cardiac stimulation devices and methods for measuring impedances associated with the left side of the heart 111 2001
7,613,513 System and method for determining cardiac geometry 0 2003
7,003,348 Monitoring cardiac geometry for diagnostics and therapy 6 2003
* 7,505,814 System and method for evaluating heart failure based on ventricular end-diastolic volume using an implantable medical device 4 2004
7,305,266 Cardiac stimulation devices and methods for measuring impedances associated with the heart 14 2004
7,627,366 Analysis of polarization information 0 2005
7,587,239 Cardiac pacemaker system, lead and method for rejecting far-field signals 0 2006
8,712,519 Closed-loop adaptive adjustment of pacing therapy based on cardiogenic impedance signals detected by an implantable medical device 2 2006
8,600,497 Systems and methods to monitor and treat heart failure conditions 2 2006
7,794,404 System and method for estimating cardiac pressure using parameters derived from impedance signals detected by an implantable medical device 12 2006
9,107,585 Tissue characterization using intracardiac impedances with an implantable lead system 0 2007
8,065,005 Tissue characterization using intracardiac impedances with an implantable lead system 2 2007
8,010,196 Tissue characterization using intracardiac impedances with an implantable lead system 3 2007
7,945,326 Tissue characterization using intracardiac impedances with an implantable lead system 1 2007
7,925,349 Tissue characterization using intracardiac impedances with an implantable lead system 3 2007
8,868,186 Methods for measuring impedances associated with the heart 0 2007
* 2008/0058,669 METHODS FOR MEASURING IMPEDANCES ASSOCIATED WITH THE HEART 1 2007
8,126,546 Anodal excitation of tissue 0 2009
* 2010/0331,906 ANODAL EXCITATION OF TISSUE 5 2009
8,306,623 Tissue characterization using intracardiac impedances with an implantable lead system 0 2011
9,113,789 System and method for estimating electrical conduction delays from immittance values measured using an implantable medical device 0 2012
9,089,276 Systems and methods for obtaining substantially simultaneous mult-channel impedance measurements and related applications 0 2013
9,066,662 System and method for estimating cardiac pressure based on cardiac electrical conduction delays using an implantable medical device 0 2013
 
BOSTON SCIENTIFIC SCIMED, INC. (1)
9,022,962 Apparatus for detecting and treating ventricular arrhythmia 0 2004
 
RHYTHNIA MEDICAL, INC. (1)
9,277,872 Electroanatomical mapping 0 2011
 
SORIN CRM S.A.S. (2)
* 6,604,002 Measuring the trans-valvular bio-impedance in an active implantable medical device, in particular a pacemaker, defibrillator and/or cardiovertor and/or multisite device 10 2001
* 6,539,261 Measurement of intracardiac impedance in a multisite-type, active implantable medical device, in particular a pacemaker, defibrillator and/or cardiovertor 39 2001
* Cited By Examiner