Compounds that inhibit the binding of RAF-1 or 14-3-3 proteins to the beta chain of IL-2 receptor, and pharmaceutical compositions containing same

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United States of America Patent

PATENT NO 6281193
APP PUB NO 20010016194A1
SERIAL NO

09194145

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to compounds, such as proteins, peptides and organic compounds, capable of blocking or inhibiting the binding interaction of Raf-1 or 14-3-3 proteins to the .beta. chain of IL-2, and pharmaceutical compositions containing such compounds. In vitro assays for isolating, identifying and characterizing such compound capable of inhibiting interaction of Raf-1 or 14-3-3 proteins to IL-2.beta. are also provided.

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Patent Owner(s)

  • APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Maslinski, Wlodzimierz Warsaw, PL 8 207
Strom, Terry Brookline, MA 10 105

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