Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds

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United States of America Patent

PATENT NO 6284273
SERIAL NO

09028385

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Abstract

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The present invention is concerned with a solid slow release oral pharmaceutical dosage unit resistant to amylase which comprises a solid dosage unit made up of an admixture of a therapeutic dosage of an orally effective pharmaceutical product, an optional polysaccharide or polyol, and cross-linked high amylose starch, wherein the cross-linking of the high amylose starch has been carried out with a covalent or non-covalent cross-linking agent with from about 0.1 g to about 30 g of cross-linking agent per 100 g of high amylose starch.

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Patent Owner(s)

Patent OwnerAddress
LABOPHARM INCQUEBEC CANADA QUEBEC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chouinard, Francois 14 Ch. D'Agremont, Lorraine, CA 13 104
Ispas-Szabo, Pompilia 3250 Forest Hill, Montreal, PQ, CA 9 89
Lenaerts, Vincent 77 Holton Avenue, Westmount, P.Q., CA 10 297
Mateescu, Mircea Alexandru 377 Sherbrooke Street West, Apt. 505, Montreal, PQ, CA 14 70

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