Assays for diagnosis of thrombophilic disease
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United States of America Patent
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Sep 4, 2001
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N/A
app pub date -
Jul 10, 1998
filing date -
Jul 11, 1997
priority date (Note) -
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Abstract
The present invention provides methods for diagnosing and/or monitoring thrombophilic disease in a patient that can result from the antiphospholipid antibody syndrome (aPL syndrome). The methods of the invention are premised on the inhibition of binding of an anticoagulant protein, annexin, preferably annexin-V, to phospholipids by antiphospholipid (aPL) antibodies in a patient blood sample.
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