Two-step pretargeting methods using improved bidtin-active agent conjugates

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United States of America Patent

PATENT NO 6287536
SERIAL NO

08788339

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Abstract

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Methods, compounds, compositions and kits that relate to pretargeted delivery of diagnostic and therapeutic agents are disclosed. In particular, methods for radiometal labeling of biotin and for improved radiohalogenation of biotin, as well as related compounds, are described. Also, clearing agents, anti-ligand-targeting moiety conjugates, target cell retention enhancing moieties and additional methods are discussed.

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Patent Owner(s)

Patent OwnerAddress
ALETHEON PHARMACEUTICALS INC2722 TRITON DRIVE SEATTLE WA 98117

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gustavson, Linda M Seattle, WA 34 497
Reno, John M Brier, WA 58 3239
Theodore, Louis J Lynnwood, WA 26 528

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