Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles
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United States of America Patent
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Sep 11, 2001
Grant Date -
N/A
app pub date -
Dec 20, 2000
filing date -
Dec 20, 2000
priority date (Note) -
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Abstract
A pharmaceutical composition comprising at least one pharmaceutically active agent that is pH dependent, at least one non-pH dependent sustained release agent, and at least one pH dependent agent that increases the dissolution rate of the at least one pharmaceutically active agent at a pH in excess of 5.5. Such compositions have minimized pH-dependent dissolution profiles or pH-independent dissolution profiles.
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