Mixed liposome pharmaceutical formulation with amphiphiles and phospholipids
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United States of America Patent
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Sep 18, 2001
Issued Date -
N/A
app pub date -
Sep 7, 1999
filing date -
Sep 27, 1998
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A mixed liposome pharmaceutical formulation with multilamellar vesicles is provided. The formulation comprises a pharmaceutical agent, water, an alkali metal alkyl sulfate, at least one membrane mimetic amphiphile, and at least one phospholipid. When aerosol delivery is intended, the formulation also comprises a propellant and a phenol. A metered dose dispenser containing the formulation, as well as a method of administering the formulation, are also provided.
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